Jordan, Eric J. and Morris, David. Evaluation of the electrosleep machine. Diseases of the Nervous System. 36(12):661-665, 1975.
9 littermate-male Beagle dogs were given 13 daily 1 hour treatments under anesthesia with eye to occipital electrodes and measured with EEG’s, ERG’s, blood pressure, temperature, respiration, blood and urine analysis. Photic stimulation was applied in addition to the CES. 3 dogs were given “normal” levels of 1 mA AC and .33 mA DC, another 3 received “high” levels of 5 mA AC and 1.33 mA DC, the third group of 3 had sham treatment.
After the course of treatment, the dogs were sacrificed and examined. 2 dogs suffered direct trauma from the citernal puncture, causing spinal cord lesions. No neurologic signs were noted from the CES. It was noted that CES may cause mild EEG slowing. Suspicious findings were found in the striate cortex, caudate nucleus, and septum. Except for 1 case, these were small and of questionable significance. There were no changes that were unequivocally pathological. No acute or chronic changes were noted in BP, EKG, temperature or respiration. The authors concluded that evidence of CES-induced pathology is inconclusive.